Fisting, too, brings the possibility of infection with HIV and Hepatitis B and C. Infection can occur if a partner has wounds on the skin of his or her hand. In this way, infected blood can enter the other partner’s body through the anal mucous membrane. Since fisting frequently causes minor or major injuries and anal and rectal bleeding, infection of the other partner is also possible.

In addition, fisting brings the risk of infection with all the sexually transmitted diseases listed under rimming.